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Volume
35, Issue 2 (February 2014)
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Special issue on Christopher Walsh - an
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The January 2014 special issue of
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Review
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EZH2: biology, disease, and structure-based drug
discovery OPEN
Jin-zhi Tan, Yan Yan,
Xiao-xi Wang, Yi Jiang and H Eric Xu
Acta
Pharmacol Sin 2014 35: 161-174; advance online publication, December 23,
2013; 10.1038/aps.2013.161
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Original Articles
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Co-activation of nAChR and mGluR induces γ oscillation in rat medial septum diagonal band of
Broca slices
Ya-li Wang, Jian-gang Wang,
Gao-xiang Ou-yang, Xiao-li Li, Zaineb Henderson and
Cheng-biao Lu
Acta
Pharmacol Sin 2014 35: 175-184; advance online publication, January 6,
2014; 10.1038/aps.2013.138
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Glutamate microinjection into the hypothalamic
paraventricular nucleus attenuates ulcerative colitis in rats
Ting-ting Li,
Jian-fu Zhang, Su-juan Fei, Sheng-ping Zhu,
Jin-zhou Zhu, Xiao Qiao and Zhang-bo Liu
Acta
Pharmacol Sin 2014 35: 185-194; advance online publication, December 23,
2013; 10.1038/aps.2013.140
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Exendin-4 ameliorates oxidized-LDL-induced inhibition
of macrophage migration in vitro via the NF-κB pathway
Ge-fei Ma, Song Chen,
Lei Yin, Xiang-dong Gao and Wen-bing Yao
Acta
Pharmacol Sin 2014 35: 195-202; advance online publication, December 16,
2013; 10.1038/aps.2013.128
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Sinomenine induces apoptosis in RAW 264.7 cell-derived
osteoclasts in vitro via caspase-3 activation
Long-gang He,
Xiang-lian Li, Xiang-zhou Zeng, Heng Duan, Song Wang,
Lin-sheng Lei, Xiao-juan Li and Shu-wen Liu
Acta
Pharmacol Sin 2014 35: 203-210; advance online publication, December 23,
2013; 10.1038/aps.2013.139
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Daptomycin exerts rapid bactericidal activity against Bacillus
anthracis without disrupting membrane integrity
Yu-hua Xing, Wei Wang,
Su-qin Dai, Ti-yan Liu, Jun-jie Tan, Guo-long Qu,
Yu-xia Li, Yan Ling, Gang Liu, Xue-qi Fu and
Hui-peng Chen
Acta
Pharmacol Sin 2014 35: 211-218; advance online publication, December 23,
2013; 10.1038/aps.2013.159
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Therapeutic effects of DZ2002, a reversible SAHH
inhibitor, on lupus-prone NZB×NZW F1 mice via interference with
TLR-mediated APC response
Shi-jun He, Ze-min Lin,
Yan-wei Wu, Bing-xin Bai, Xiao-qian Yang, Pei-lan He,
Feng-hua Zhu, Wei Tang and Jian-ping Zuo
Acta
Pharmacol Sin 2014 35: 219-229; advance online publication, December 30,
2013; 10.1038/aps.2013.167
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Microvesicles secreted from human multiple myeloma
cells promote angiogenesis
Yan Liu, Xiao-jian Zhu,
Chen Zeng, Pin-hui Wu, Hong-xiang Wang, Zhi-chao Chen
and Qiu-bai Li
Acta
Pharmacol Sin 2014 35: 230-238; advance online publication, December 30,
2013; 10.1038/aps.2013.141
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Inhibition of EGFR autophosphorylation plays an
important role in the anti-breast cancer efficacy of the dithiocarbamate
derivative TM208
Xi-wei Ji, Run-tao Li,
Zai-quan Li, Liang Li, Xue-yan Shao, Si-yuan Wang,
Yin Yuan, Tian-yan Zhou and Wei Lu
Acta
Pharmacol Sin 2014 35: 239-247; advance online publication, December 30,
2013; 10.1038/aps.2013.156
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Antitumor effects of concanavalin A and Sophora
flavescens lectin in vitro and in vivo
Zheng Shi, Jie Chen,
Chun-yang Li, Na An, Zi-jie Wang, Shu-lin Yang,
Kai-feng Huang and Jin-ku Bao
Acta
Pharmacol Sin 2014 35: 248-256; advance online publication, December 23,
2013; 10.1038/aps.2013.151
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Mangiferin activates Nrf2-antioxidant response element
signaling without reducing the sensitivity to etoposide of human myeloid
leukemia cells in vitro: a novel Nrf2 activator without a “dark
side”
Ben-ping Zhang, Jie Zhao,
Shan-shan Li, Li-jing Yang, Ling-lan Zeng, Yan Chen
and Jun Fang
Acta
Pharmacol Sin 2014 35: 257-266; advance online publication, December 30,
2013; 10.1038/aps.2013.165
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S-allylcysteine, a garlic derivative, suppresses
proliferation and induces apoptosis in human ovarian cancer cells in
vitro
Ya-si Xu, Jian-guo Feng,
Dan Zhang, Bo Zhang, Min Luo, Dan Su and
Neng-ming Lin
Acta
Pharmacol Sin 2014 35: 267-274; advance online publication, December 23,
2013; 10.1038/aps.2013.176
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Bioavailability, tissue distribution, and excretion
characteristics of the novel carbonic anhydrase inhibitor
tolsultazolamide in rats
Jin-da Wang, Yong-ping Shi,
Jing Yin, Zhi-yuan Pan, Wen-yu Cui, Yan-fang Zhang
and Hai Wang
Acta
Pharmacol Sin 2014 35: 275-282; advance online publication, December 16,
2013; 10.1038/aps.2013.146
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Phorbol 12-myristate 13-acetate inhibits
P-glycoprotein-mediated efflux of digoxin in MDCKII-MDR1 and Caco-2 cell
monolayer models
Yu-hua Li, Hui-chang Bi,
Ling Huang, Jing Jin, Guo-ping Zhong, Xu-nian Zhou
and Min Huang
Acta
Pharmacol Sin 2014 35: 283-291; advance online publication, December 23,
2013; 10.1038/aps.2013.157
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Hepatic cytochrome P450s play a major role in
monocrotaline-induced renal toxicity in mice
Jun Yao, Cheng-gang Li,
Li-kun Gong, Chen-chen Feng, Chun-zhu Li, Man Gao,
Yang Luan, Xin-ming Qi and Jin Ren
Acta
Pharmacol Sin 2014 35: 292-300; advance online publication, December 23,
2013; 10.1038/aps.2013.145
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Structure-based ensemble-QSAR model: a novel approach
to the study of the EGFR tyrosine kinase and its inhibitors
Xian-qiang Sun, Lei Chen,
Yao-zong Li, Wei-hua Li, Gui-xia Liu, Yao-quan Tu and
Yun Tang
Acta
Pharmacol Sin 2014 35: 301-310; advance online publication, December 16,
2013; 10.1038/aps.2013.148
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